Domini is an award-winning chef, food writer and entrepreneur. She is a co-founder of ITSA, Hatch & Sons, Alchemy Juice Co and Joe's, as well as Feast catering & events. She is joint-MD of the ITSA food group and runs the company with her sister, Peaches, since 1999. The sisters were finalists of the E&Y entrepreneur of the year, and winners of the Image Businesswoman of the year. They oversee multiple restaurant, cafes and event catering operations.

Domini is a Euro-toques chef and was awarded her MA in Gastronomy and Food Studies in 2019. She also developed the PEP Entrepreneur Programme in Wheatfield Prison, which was recently turned into a 4- part documentary, "Prison Breaks" on Virgin Media, looking at ways to reduce the cost of recidivism through entrepreneurial activities for prisoners upon release.

Domini is author of five cookbooks and was the Irish Times food writer from 2008-2016. Her fifth cookbook, "The Ketogenic Kitchen", has been a best-seller in Ireland and the US. She has presented to health care professionals both in Ireland and Switzerland as a patient advocate on topics of food, cancer and the concept of food as medicine. She is completing the Chartered Director Diploma in the IoD and a Diploma in Culinary Medicine. She has completed a Pg Dip in Positive Health in the Royal College of Surgeons, Dublin – focusing on integrated and lifestyle medicine. She regularly contributes to TV and radio and consults on various restaurant and food projects.